Evaluation of the effect of intravenous ibuprofen use on postoperative pain and opioid consumption after abdominoplasty operation

  • Mustafa Turkoglu Department of Anesthesiology and Reanimation, Bolu Abant Izzet Baysal University, Faculty of Medicine, Bolu, Turkey http://orcid.org/0000-0002-4220-4621
  • Isa Yildiz Department of Anesthesiology and Reanimation, Bolu Abant Izzet Baysal University, Faculty of Medicine, Bolu, Turkey http://orcid.org/0000-0001-7476-2217
  • Ali Gokkaya Department of Plastic and Aesthetic Surgery, Bolu Abant Izzet Baysal University, Faculty of Medicine, Bolu, Turkey http://orcid.org/0000-0003-2710-9615
  • Akın Disikirik Department of Anesthesiology and Reanimation, Bolu Abant Izzet Baysal University, Faculty of Medicine, Bolu, Turkey http://orcid.org/0000-0003-1174-557X
  • Abdullah Demirhan Department of Anesthesiology and Reanimation, Bolu Abant Izzet Baysal University, Faculty of Medicine, Bolu, Turkey http://orcid.org/0000-0003-4139-5080
Keywords: Abdominoplasty, postoperative pain, ibuprofen, opioids

Abstract

Aim: Abdominoplasty is a common cosmetic procedure that is one of the most painful aesthetic surgery and has been used increasingly in recent years. Ibuprofen is a non-steroidal anti-inflammatory (NSAID) with antipyretic and analgesic effects. In this study, we aimed to evaluate the effectiveness of the intravenous (IV) form of ibuprofen on postoperative pain control and opioid requirement in patients who underwent abdominoplasty.

Methods: The patients were divided into 3 groups as Group 1 (Tramadol), Group 2 (Ibuprofen) and Group 3 (Tramadol HCL + Ibuprofen). Tramadol HCL was given continuous infusion at a concentration of 4mg / ml via IV Patient Controlled Analgesia to Group 1. Ibuprofen 800 mg IV was administered to Group 2 at 30 minutes before the end of the operation. Patients were followed up by administering 800 mg IV every 6 hours for 24 hours. In Group 3, 30 minutes before the end of the operation, tramadol was administered via PCA with continuous infusion at a concentration of 4mg / ml and 800 mg IV ibuprofen was administered as 4x1.

Results: VAS values ​​were found to be significantly lower in Group 3 compared to Group 2 at every hour and at the 4th hour compared to Group 1. Group 3 was found to be significantly lower than Group 1 in total analgesic consumption in all time zones.

Conclusion: We think that IV ibuprofen, which will be given in addition to tramadol after abdominoplasty, can provide effective analgesia and reduce analgesic consumption.

Published
2021-12-26
How to Cite
Turkoglu, M., Yildiz, I., Gokkaya, A., Disikirik, A., & Demirhan, A. (2021, December 26). Evaluation of the effect of intravenous ibuprofen use on postoperative pain and opioid consumption after abdominoplasty operation. EXPERIMENTAL BIOMEDICAL RESEARCH, 5(1), 98-105. https://doi.org/https://doi.org/10.30714/j-ebr.2022173854