The effect of atherogenic plasma index on collateral development in patients with chronic coronary total occlusion

Keywords: Coronary artery, occlusion, collateral vessels, atherogenic plasma index, triglyceride/HDL ratio

Abstract

Aim: To demonstrate the correlation between coronary collateral circulation (CCC) and atherogenic plasma index (AIP), one of the factors associated with the formation of collateral vessels.

Methods: Hospital records of patients with chronic total occlusion (100% stenosis) in at least one coronary artery were evaluated. Triglycerides, HDL level, triglyceride/HDL ratio and atherogenic plasma index before coronary angiography were assessed for the 451 patients who met the study criteria.

Results: Comparison of the two groups in terms of laboratory findings showed that triglyceride/HDL ratio (5.04±3.13 vs 3.56±2.12, p<0.001) and AIP (0.63±0.25 vs 0.48±0.25, p<0.001) were higher with statistical significance in the weak collateral group. The ROC analysis revealed an association between weak collateral formation and atherogenic plasma index with 64.7% sensitivity and 66.2% specificity using a cut-off value of 0.58 for AIP. Accordingly, low AIP was found to be an independent predictor of good collateral artery formation.

Conclusion: This study suggests that a high atherogenic plasma index may be an independent factor associated with poor collateral formation.

Published
2021-09-21
How to Cite
Guzel, T., Bilik, M., Arslan, B., Kilic, R., & Aktan, A. (2021, September 21). The effect of atherogenic plasma index on collateral development in patients with chronic coronary total occlusion. EXPERIMENTAL BIOMEDICAL RESEARCH, 4(4), 291-301. https://doi.org/https://doi.org/10.30714/j-ebr.2021471924