Investigation of a healthcare-associated candida infections in a Turkish intensive care unit: risk factors, therapy and clinical outcome

  • Fatma Avcioglu Department of Medical Microbiology, Bolu Abant Izzet Baysal University, Faculty of Medicine, Bolu, Turkey http://orcid.org/0000-0002-6011-7775
  • Fatma Sirmatel Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Turkey http://orcid.org/0000-0003-0442-5981
  • Mustafa Behcet Department of Medical Microbiology, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Turkey http://orcid.org/0000-0002-5676-6983
  • Ogulcan Ozarslan Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Turkey http://orcid.org/0000-0002-2635-7011
  • Hasan Tahsin Gozdas Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Turkey http://orcid.org/0000-0003-3857-685X
Keywords: Candida, health care, intensive care unit, candidiasis, mortality

Abstract

Aim: Candida infections develop especially in intensive care unit (ICU) patients and increase the mortality rates. So, early and accurate diagnosis of Candida infections and determination of risk factors are very important. We aimed to retrospectively investigate Candida infections in terms of species and risk factors for candidemia caused by fungi.

Methods: Candida infections in critically ill patients hospitalized in the ICU between January 2014 and December 2018 at Bolu Abant Izzet Baysal University Training and Research Hospital were retrospectively analyzed. The isolated Candida species were evaluated according to the sample types. The cases were investigated in terms of mortality due to candidiasis, previously used antibiotics and isolated Candida species.

Results: 34 Candida species isolated from fungal cultures in ICUs were included in the study. Candida albicans (73.5%) was the most prevalent species isolated (NAC 26.5%). Patients with Candida isolated in their urine samples (76%) had a higher mortality rate than patients with Candida from other regions.

Conclusion: The results of our study suggest that the highest rate of candidiasis (88%) is in patients who received beta-lactam antibiotic treatment. In addition, we think that when Candida species are detected in the urine samples of critically ill patients in the ICU, care should be taken in terms of candidiasis.

Published
2020-12-28
How to Cite
Avcioglu, F., Sirmatel, F., Behcet, M., Ozarslan, O., & Gozdas, H. (2020, December 28). Investigation of a healthcare-associated candida infections in a Turkish intensive care unit: risk factors, therapy and clinical outcome. EXPERIMENTAL BIOMEDICAL RESEARCH, 4(1), 9-15. https://doi.org/https://doi.org/10.30714/j-ebr.2021165773