Does hemogram biomarkers predict mortality in intensive care population?

Abstract

Aim: To compare hemogram-mediated inflammatory markers such as mean platelet volume (MPV), red cell distribution width (RDW), platelet distribution width (PDW), neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), MPV to platelet ratio (MPR) and RDW to platelet ratio (RPR) in predicting outcome in the intensive care units (ICU) population.

Methods: After obtaining approval of intuitional board the patients whom were treated in the Anesthesiology and Reanimation ICU of Bolu Abant Izzet Baysal University Hospital between March 2017 and December 2018 were evaluated retrospectively and enrolled to the study. The above-mentioned laboratory parameters of the deceased and survivors were compared.

Results: The PDW, MPV, C-reactive protein (CRP), RPR and MPR values were significantly different between deceased and survived subjects. Moreover, MPV and PDW values ​​were significantly and positively correlated with serum CRP level.

Conclusion: We suggest that PDW, MPV, MPR and RPR could be used in determining the severity of the disease in ICU patients along with CRP. Since these hemogram results could be obtained in a much shorter time period compared to CRP, they could be useful in this population; in which hours and even minutes are important in the treatment in ICU.