Is Helicobacter pylori prevalence associated with the family population?

Abstract

Aim: To investigate the incidence of Helicobacter pylori (H. pylori) and related lesions in patients who applied to the gastroenterology outpatient clinic of our institution and its relationship with the family population.

Methods: The data of 701 patients who underwent elective esophagogastroduodenoscopy and were suitable for H. pylori research were analyzed. The patients were classified according to gender and age groups (under 40 years of age and above) and evaluated for H. pylori, gastric atrophy and intestinal metaplasia by histopathological method. In addition, the relationship between H. pylori and gastric atrophy, intestinal metaplasia, family population, total income of the family, and gender were investigated.

Results: Intestinal metaplasia was found in 3.1% of women and 6.6% of men (p=0.03). H. pylori positivity was found as 65% in the group under 40 and 54% in the group over 40 years old (p = 0.003). Atrophy was detected as 2% in the group under 40 years of age and 13.1% in the group over 40 years old (p <0.001). There was no difference between the H. pylori positive group and the H. pylori negative group in terms family populations (p>0.05).

Conclusion: Our current findings from our study do not suggest that the prevalence of H. pylori is related to the number of family members, but we think that intestinal metaplasia is more common in males than females, and the eradication of H. pylori in this population should be detailed.