@article{Ozcan_Akin_Kose_Coskun_Uluc_Gorgel_Yilmaz_Yagli_2020, title={The efficacy of multiparametric prostate magnetic resonance imaging in the diagnosis and treatment of prostate cancer}, volume={3}, url={https://experimentalbiomedicalresearch.com/ojs/index.php/ebr/article/view/104}, DOI={10.30714/j-ebr.2020361052}, abstractNote={<p><strong>Aim: </strong>To investigate the accuracy of multiparametric prostate magnetic resonance imaging (mpMRI) in determining the diagnosis and treatment options of prostate cancer (PCa), and its pathology correlation.</p> <p><strong>Methods: </strong>Between October 2017 and January 2018, 73 patients were subjected to an mpMRI at our clinic. Of these patients, 11 were radical prostatectomy (RP) after treatment, and four were post- radiation therapy<strong> (</strong>RT) follow-up. The remaining 58 patients were assigned to the PSA elevation and / or positive digital rectal examination (<em>DRE</em>) patient group in this study and their outcomes were evaluated.</p> <p><strong>Results: </strong>Of the 58 patients included in the study, 13 were found to have a PI-RADS 5 on mpMRI and in 9 (90%) of 10 patients undergoing simultaneous biopsy, PCa was detected. The biopsy results of all cases evaluated as PI-RADS 1 were benign. All of the patients who were ISUP 3 and above had a PI-RADS 5. Patients with a PI-RADS score of 4 and above being ISUP 2 and above was statistically significant <em>(p=0.011)</em>. A case had undergone a previous radical prostatectomy assessment revealed that tPSA increased to 2 ng/ml during the follow-up, and so RT was added to the treatment; although LAP was identified in the left iliac region on an mpMRI performed upon the continued increase of tPSA. During the follow-ups of the patient who had regional RT, the tPSA dropped below 0.01 ng/ml.</p> <p><strong>Conclusion: </strong>The results of our study show that mpMRI can gain a new and important place in urology due to the guidance it provides in biopsies, facilitating targeted biopsy, its effectiveness in determining treatment modalities and its importance in post-PCa treatment follow-ups.</p>}, number={3}, journal={EXPERIMENTAL BIOMEDICAL RESEARCH}, author={Ozcan, Serkan and Akin, Yiğit and Kose, Osman and Coskun, Mehmet and Uluc, Muhsin Engin and Gorgel, Sacit Nuri and Yilmaz, Yuksel and Yagli, Omer Faruk}, year={2020}, month={Jun.}, pages={167–175} }