A comprehensive review on rational and effective treatment strategies against an invisible enemy; SARS Cov-2 infection

Abstract

The year 2020 is began with the declaration of a pandemic of novel coronavirus, which first occurred by the end of 2019 in Wuhan region of China. The novel virus infection is so called as Covid-19 or SARS Cov-2. The infection rapidly spread all over the world and changed the lives of millions. In this extended review, we aimed to discuss current and possible treatment strategies against SARS Cov-2 infection. Treatment options mentioned here include but not limited to chloroquine/hydroxychloroquine, favipiravir, remdesivir, lopinavir/ritonavir, umifenovir, steroids, cepharanthine, convalescent plasma, anticoagulants and monoclonal antibodies. In conclusion, mainstay of the SARS Cov-2 treatment is general measures such as patient isolation and supportive care. However, encouraging developments are being achieved in terms of discovery of an effective treatment and production of a potent vaccine.